The pseudoknot region and poly-(C) tract comprise an essential RNA packaging signal for assembly of foot-and-mouth disease virus.
Virus assembly is a crucial step for the completion of the viral replication cycle.In addition to ensuring efficient incorporation of viral genomes into nascent virions, high specificity is required to prevent incorporation of host nucleic acids.For picornaviruses, including FMDV, the mechanisms required to fulfil these requirements are not well un